Binbin Cheng Selected Research

dibenzyl ether

12/2020

Discovery of Novel and Highly Potent Resorcinol Dibenzyl Ether-Based PD-1/PD-L1 Inhibitors with Improved Drug-like and Pharmacokinetic Properties for Cancer Treatment.

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Binbin Cheng Research Topics

Disease

16	Neoplasms (Cancer) 07/2022 - 06/2012
7	Hepatocellular Carcinoma (Hepatoma) 01/2021 - 03/2011
3	Hypoxia (Hypoxemia) 01/2021 - 01/2019
3	Liver Neoplasms (Liver Cancer) 01/2019 - 12/2010
3	Inflammation (Inflammations) 12/2016 - 07/2011
2	Skin Diseases (Skin Disease) 01/2022 - 01/2020
2	Osteoporosis 05/2012 - 07/2011
1	Neoplasm Metastasis (Metastasis) 01/2021
1	Fibrosis (Cirrhosis) 01/2020
1	Bites and Stings (Sting) 09/2018
1	Carcinogenesis 09/2018
1	Non-alcoholic Fatty Liver Disease 02/2018
1	Colonic Neoplasms (Colon Cancer) 01/2018
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2018
1	Yin Deficiency (Yinxu) 01/2017
1	Nevus (Nevi) 01/2017
1	Leukemia 02/2015
1	Breast Neoplasms (Breast Cancer) 02/2015
1	Proteinuria 01/2015
1	Hyperglycemia 07/2011
1	Hepatoblastoma 03/2011
1	Infections 12/2010

Drug/Important Bio-Agent (IBA)

4	Proteins (Proteins, Gene)FDA Link 01/2021 - 06/2012
3	Messenger RNA (mRNA)IBA 01/2021 - 01/2017
3	LigandsIBA 01/2021 - 09/2018
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2021 - 01/2019
2	DNA (Deoxyribonucleic Acid)IBA 07/2022 - 02/2022
2	Paclitaxel (Taxol)FDA LinkGeneric 03/2021 - 01/2021
2	Pharmaceutical PreparationsIBA 03/2021 - 12/2020
2	resorcinol (resorcin)IBA 01/2021 - 12/2020
2	Immune Checkpoint InhibitorsIBA 01/2021 - 12/2020
2	Interleukin-8 (Interleukin 8)IBA 01/2021 - 01/2021
2	DiosgeninIBA 02/2018 - 02/2015
2	Dexamethasone (Maxidex)FDA LinkGeneric 12/2016 - 07/2011
2	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 12/2016 - 07/2011
2	Proto-Oncogene Proteins c-metIBA 03/2011 - 12/2010
1	AZD7648IBA 07/2022
1	Biological ProductsIBA 07/2022
1	Doxorubicin (Adriamycin)FDA LinkGeneric 07/2022
1	1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA 07/2022
1	olaparibIBA 02/2022
1	Poly(ADP-ribose) Polymerase InhibitorsIBA 02/2022
1	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA 01/2022
1	Transcription Factors (Transcription Factor)IBA 01/2022
1	Peptides (Polypeptides)IBA 03/2021
1	TubulinIBA 03/2021
1	Cell-Penetrating PeptidesIBA 03/2021
1	6-chloro-2-(1-piperazinyl)pyrazine (CPP)IBA 03/2021
1	thiamine triphosphorate (TTP)IBA 03/2021
1	EnzymesIBA 01/2021
1	Glutamine (L-Glutamine)FDA Link 01/2021
1	Colchicine FDA LinkGeneric 01/2021
1	ImmunosorbentsIBA 01/2021
1	RNA (Ribonucleic Acid)IBA 01/2021
1	N-methyladenosineIBA 01/2021
1	LuciferasesIBA 01/2021
1	diphenyl (biphenyl)IBA 01/2021
1	CytokinesIBA 01/2021
1	Ether (Diethyl Ether)IBA 01/2021
1	Programmed Cell Death 1 ReceptorIBA 12/2020
1	dibenzyl etherIBA 12/2020
1	Monoclonal AntibodiesIBA 12/2020
1	Keratins (Keratin)IBA 01/2020
1	CollagenIBA 01/2020
1	Hydroxyproline (4 Hydroxyproline)IBA 01/2020
1	Filaggrin ProteinsIBA 01/2020
1	levistilide AIBA 01/2020
1	loricrinIBA 01/2020
1	AngiotensinsIBA 01/2020
1	Matrix Metalloproteinases (MMPs)IBA 01/2019
1	Melitten (Melittin)IBA 01/2019
1	Sorafenib (BAY 43-9006)FDA Link 10/2018
1	Chemokine ReceptorsIBA 09/2018
1	AntibodiesIBA 09/2018
1	Toll-Like Receptors (Toll-Like Receptor)IBA 09/2018
1	Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA 09/2018
1	Tretinoin (Retinoic Acid)FDA LinkGeneric 09/2018
1	InterferonsIBA 09/2018
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2018
1	SaponinsIBA 01/2018
1	SteroidsIBA 01/2018
1	dioscinIBA 01/2018
1	Liuwei Dihuang DecoctionIBA 01/2017
1	Actins (F Actin)IBA 01/2017
1	GlucocorticoidsIBA 12/2016
1	AutoantibodiesIBA 01/2015
1	ginsenoside Rh1IBA 05/2014
1	Cyclin B1IBA 06/2012
1	Biomarkers (Surrogate Marker)IBA 06/2012
1	GinsenosidesIBA 05/2012
1	Mitogen-Activated Protein KinasesIBA 05/2012
1	ginsenoside Rb1IBA 05/2012
1	Small Interfering RNA (siRNA)IBA 12/2010
1	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 12/2010

Therapy/Procedure

3	Therapeutics 07/2022 - 10/2018
2	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2021 - 01/2021
2	Immunotherapy 01/2021 - 09/2018